Optimal Antihypertensive Combination Treatments HYPERTENSION | REVIEW
نویسندگان
چکیده
Current recommendations from international guidelines strongly emphasise the need to achieve target BP levels as promptly as possible in all hypertensive patients [1, 12, 13]. These thresholds, however, may vary depending on the individual patient’s total (or global) CV risk. It is this risk profile, therefore, that should influence the assessment of what would constitute an acceptable target BP, how aggressively it will be pursued and the choice among different classes and dosages of antihypertensive medications used to achieve this goal. When treating low-risk hypertensive patients, the aim should be to reduce the systolic BP value to <140 mmHg and the diastolic BP value to <90 mmHg.
منابع مشابه
Fixed-dose triple-combination treatments in the management of hypertension.
Hypertension remains uncontrolled in approximately 50% of patients with hypertension, which increases the risk of cardiovascular morbidity and mortality in these individuals. A key factor contributing to poor blood pressure (BP) control is nonadherence to prescribed antihypertensive medications. Improving patient adherence to antihypertensive therapy is the key to improving BP goal attainment. ...
متن کاملHIV: A fragile population enters managed care.
Hypertension remains uncontrolled in approximately 50% of patients with hypertension, which increases the risk of cardiovascular morbidity and mortality in these individuals. A key factor contributing to poor blood pressure (BP) control is nonadherence to prescribed antihypertensive medications. Improving patient adherence to antihypertensive therapy is the key to improving BP goal attainment. ...
متن کاملManagement of Hypertension Using Olmesartan Alone or in Combination
Hypertension is one of the most significant and consistent risk factors for many cardiovascular diseases. The global prevalence of hypertension has dramatically increased over recent years. Life-style and genetic factors are generally considered to be primarily responsible for the incidence of hypertension. Concerning the high morbidity rate, setting up an updated standard for hypertensive pati...
متن کاملClinical utility of fixed-dose combinations in hypertension: evidence for the potential of nebivolol/valsartan
Despite significant advances in pharmacologic approaches to treat hypertension during the last decades, hypertension- and hypertension-related organ damage are still a high health and economic burden because a large proportion of patients with hypertension do not achieve optimal blood pressure control. There is now general agreement that combination therapy with two or more antihypertensive dru...
متن کاملThe first hypertension trial comparing the effects of two fixed-dose combination therapy regimens on cardiovascular events: Avoiding Cardiovascular events through Combination therapy in Patients Living with Systolic Hypertension (ACCOMPLISH).
Current recommendations for the treatment of hypertension clarify the need to achieve lower blood pressure levels in the general population (<140/90 mm Hg) and in specific high-risk patient groups such as patients with diabetes or chronic renal disease (<130/80 mm Hg). Further, it is evident that to reach appropriate blood pressure control, most patients with high blood pressure will require tw...
متن کامل